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The alpha-glucosidase inhibitor Acarbose induces a reversible delay of carbohydrate digestion. An HPLC-UV method has been developed for the determination of valibose, miglitol, voglibose and Acarbose, the four anti-diabetic drugs. Cost-Effectiveness of Dapagliflozin versus Acarbose as a Monotherapy in Type 2 Diabetes in China.

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Acarbose is used (with diet only or diet and other medications) to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Acarbose works by slowing the action of certain chemicals that break down food to release glucose (sugar) into your blood. Slowing food digestion helps keep blood glucose from rising very high after meals.

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

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To determine whether nasal continuous positive airway pressure (CPAP) changes awake upper airway morphology in obstructive sleep apnea (OSA), we performed awake upper airway MRI scans on five male patients with moderate to severe OSA before and after 4 to 6 wk of nasal CPAP therapy. The accuracy required in the measurement of output is an issue that has as yet still not been satisfactorily addressed in empirical research on efficiency in primary health care. On repeat testing 2 years later, 11/15 group A patients and 3/5 group B patients tested negative for BHR.

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In vitro susceptibilities of Plasmodium falciparum to compounds which inhibit nucleotide metabolism. This study demonstrates that the regions of the developing mouse placenta produce specialized extracellular matrices which may contain different ratios of these polypeptides. Awareness of gender differences among the students in addition to faculty enthusiasm communicates positive professional attitudes.

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The authors describe a case of cerebral haemorrhage associated with haemophilia A--their own observation, findings and confrontation with data in the literature. The time is ripe: A general theoretical framework based on force-transformed potential energy surfaces rationalizes the intriguing results of recent experiments in the emerging field of covalent mechanochemistry.

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These results also suggest that additional opportunities exist across countries to improve severe sepsis outcomes. Despite having pharmacodynamic or target activity, many drugs fail in the drug development process due to poor bioavailability, and presently marketed conventional dosage forms of poorly soluble drugs employ high doses leading to potential toxicity. rapa sequences and the Arabidopsis genome, it appears that polyploidy and chromosomal diploidization are ongoing processes that collectively stabilize the B. Identification of modifiable psychosocial characteristics related to survival of heart transplant (HTx) candidates is needed to prevent clinical deterioration and improve prognosis. Skin blood flow and its oscillatory components in patients with acute myocardial infarction.

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Glycoconjugates in the mucosa of the digestive tract of Cynoscion guatucupa: a histochemical study. Posterior sagittal pararectal approach with rectal mobilization for repair of rectourethral fistula: an alternative approach. Effect of metal ion exchange on the photocurrent response from bacteriorhodopsin on tin oxide electrodes. This combination may not be as rare as it has been previously reported. In mouse splenic B cells, we find that AID-dependent DSBs occur in Smu mainly in the G(1) phase of the cell cycle, indicating they are not created by replication across SSBs.

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The cuff is wrapped around a blood vessel for real-time blood pressure monitoring. Role of unilateral adrenalectomy in bilateral primary aldosteronism: a 22-year single center experience. Exogenous insulin use in DM2 patients may contribute to increased plaque vulnerability by stimulating local angiogenesis within atherosclerotic plaques.

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These changes in patients with phenylketonuria resemble those observed in vegetarians and may be due to the absence of preformed arachidonic acid and long-chain n-3 fatty acids in the phenylketonuric diet. Recent developments of acupuncture in Australia and the way forward.

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Internal medicine housestaff, hospitalists, and nonhospitalist internal medicine faculty. Type IVa SCCmec did not carry any of the multiple antibiotic resistance genes reported in type II SCCmec. Growth environment and sex differences in lipids, body shape and diabetes risk.

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Incidence of AF is reduced, but not eliminated by prophylaxis with beta-blockers. Most advances in conventional diagnostic imaging techniques have focused on improving the spatial resolution and speed of acquisition of images or on new contrast agents.

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Imaging techniques revealed a cyst-like structure originating from a degenerated symphysis pubis. Methods are detailed for expressing and purifying fusion proteins that are used to isolate substrate mRNPs employing differential display technology.

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Identification of Xanthomonas campestris and its pathovars requires pathogenicity tests in addition to phenotypic and molecular characterization. A high concentration of XAip1 bound along the length of the filament.

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Identification of a prolonged, corrected QT (QTc) interval in athletes may be a recommendation for disqualification from competitive sports. The effects of methoxamine and epinephrine on survival and regional distribution of cardiac output in dogs with prolonged ventricular fibrillation.

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This paper presents results of blood pressure dynamicity analysis aimed at vessel stiffness detection and subsequent cardiac risk stratification. It is occasionally associated with additional signs such as facial weakness, vocal cord paralysis, weakness of the diaphragm, and pyramidal signs. This makes prediction of target site concentrations of the two species difficult.(ABSTRACT TRUNCATED AT 250 WORDS)

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The genealogy of mtDNA haplotypes was reconstructed and nested clade analysis of geographical distances was performed. Using this new, reliable and reproducible method we can answer questions they were almost impossible in the past. Carcinomas of the external auditory canal are rare, nevertheless they are associated with a relatively poor prognosis.

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In 2003, the University of Florida (UF) College of Veterinary Medicine (CVM) created an Office of International Programs (OIP) in response to one of ten initiatives of the UF Strategic Plan: internationalization of the curriculum. The diagnosis can only be arrived at after having excluded all the other possible causes of jaundice which are mentioned in the text. When the recurring event is detectable only by an expensive or invasive examination, only the number of events occurring between follow-up times may be available. Calcium channels are implicated because of the reversibility of aminoglycoside-induced changes in the cochlear microphonic by calcium and other divalent cations. To study if back pain preoperatively is associated with differences in central sensory processing, we measured transcutaneous electric sensation, pain detection and pain tolerance thresholds at the upper arm, lower back and lower leg in 52 consecutive patients scheduled for back surgery in a blinded, prospective fashion.

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The molecular and cellular events involved in SC expression, its intravesicular transport together with its polymeric IgA ligand to the apical surface of the epithelial cell, during which IgA becomes covalently linked to SC, and the proteolytic cleavage of SC from the apical membrane to release S-IgA into the lumen have been elucidated. We review comparative protein structure modeling and discuss the incorporation of physical considerations into the modeling process. The results demonstrate that the inhibition of inflammation impairs bacterial clearance from the kidneys. The Medicare Fee Schedule will be based on three components: the Resource Based Relative Value Scale (RBRVS), a conversion factor, and a geographic adjustment factor, known as the geographic practice cost index (GPCI). Undergraduates were presented targets on two occasions, and each time they were asked to choose one of two alternatives (past or future) associated with the targets in the orienting task, followed by an unexpected free recall.

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Enhancement of lymphocyte migration and cytokine production by ephrinB1 system in rheumatoid arthritis. We trust that this technique will prove to be powerful for measuring the extinction coefficients of weakly absorbing materials. Leaching of amphoteric metals was significantly affected by pH, which was a function of other studied factors. Loeys-Dietz syndrome in pregnancy: a case description and report of a novel mutation. A rational therapy of the chronic cardiac insufficiency should be performed according to a certain scheme, in which case the knowledge of the basic disease is necessary for the causal treatment.

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A treatment planning study was performed to evaluate the performance of new radiotherapy techniques based on non-coplanar multiple fields or on dynamic conformal arcs for early stage breast treatments. It was decreased significantly by 2 days when compared with explants cultured in the presence of DHT and significant differences persisted through 8 days. Energy metabolism in maximum and submaximum performance at high altitudes. Advanced techniques such as hyperspectral imaging and spectral unmixing can be applied to essentially remove this autofluorescent signal contribution, and this work attempts to quantify the effectiveness of autofluorescence spectral unmixing in a tumour xenograft model. Maximum removal of coliforms was achieved under conditions of high solar radiation and temperature.

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Given the MANOVA-based scoring method, we performed a greedy search to identify the subnetworks with the maximum scores in the PPI network. Plasmacytic leukemia---characteristics of the size and shape of atypical plasma cells in 3 cases It prevents vesicoileal reflux and allows for unimpeded efflux of urine into the bladder. By contrast, a S824D mutation of KAP1, which mimics constitutive phosphorylation of KAP1, leads to a decrease of KAP1 sumoylation and stimulation of p21 transcription before the exposure of Dox.

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Recent evidence has brought into question the efficacy of systemic corticosteroid therapy as an element of inpatient care for viral-induced wheezing. Despite this burden we found CV risk factors were inadequately managed. Surgeons may sample suspicious regional lymph nodes, but the lymph node status of many patients with renal cell carcinoma remains unknown, termed stage pNx. The study is carried out experimentally using a gaseous pilot plant as the process, in which the dynamic of such a plant exhibits the typical dynamic of an interacting series process.

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Genotypic approach to the study of bacterial resistance to antibiotics. The minimal solubilizing molar ratio between hGH and protamine was found to be at least 1:23 (hGH:protamine) by turbidity and dynamic light scattering (DLS) measurements.

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Genistein, at 25, 50, and 100 microM, and daidzein, at 25 and 50 microM, did not induce cell injury to Caco-2 cells. New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis. In vivo splicing results indicate that MBNL-regulated splicing is dependent upon the formation of stem-loops recognized by MBNL. As the hair follicles represent a good long-term reservoir for topically applied substances, it can be assumed that they also represent a reservoir for microorganisms residing on and in the skin. Infusion of either PGI2 or PGE2 (1-100 microM) released CGRP-LI in a dose-dependent manner and with a similar potency.

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These male-specific forms disappeared in male rat liver at 104 weeks of age. It receives monosynaptic EPSPs from interganglionic, cerebral-to-buccal mechanoafferent (ICBM) neurons and monosynaptically excites buccal cells, some of which are also excited by the ICBMs. These differences were not noted in patients with NSTEMI regardless of IRA. This is the first report on C6 PSO and spinal osteotomies in whole spine segments. The analysis of the line enables its use in breeding programs and in genetic studies.

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Evaluation of right ventricular function during exercise can also contribute to the assessment of patients with mitral insufficiency. Class I MHC molecules also bind immunogenic peptides, but these are derived from proteins synthesized within the target cell. The use of ultrasound-guided methods and prescribed training for cannulation skills are evidence-based practice recommendations. These findings suggest that repeated painful immersions trigger local opioid release in participants who tolerate only brief immersions, and elicit central or systemic opioid release in participants who tolerate longer immersions.

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Connecting long distance: semantic distance in analogical reasoning modulates frontopolar cortex activity. The Microbe browser is a web server providing comparative microbial genomics data.

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Although the prevalence of obstructive sleep apnea/hypopnea syndrome (OSAHS) is high in patients with acute coronary syndromes (ACS), there is little knowledge about the persistence of OSAHS in ACS patients after the acute event. The role of extracellular matrix in the morphogenesis and differentiation of salivary glands. Understanding how individual disease-associated ATG genes function will lead to a better understanding of and potentially novel therapies for treating the diseases in which they are involved. Of the 13 patients entered, 8 are alive without evidence of disease and 5 have recurred, all exclusively outside the treatment fields. By contrast, insulin is the growth factor of the Tr stimulating mitogenesis and down-regulating metabolic responses.

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A high rate of pathological gambling (11 percent) was found among patients with a secondary diagnosis of psychoactive substance use disorders. The characteristics required of flap tissue are described, such as surface characteristics, ability to restore sense of touch, cosmetic appearance, ability to close deep volume defects, and potential for revascularization of adjacent tissue.

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To identify the CDC25 gene product, we raised antibodies against two hybrid proteins, encoded by in-frame fusions between the E. Most ageing and elderly men are in a relationship and many are sexually active. Cost effectiveness analysis of azithromycin and doxycycline for Chlamydia trachomatis infection in women: A Canadian perspective. Bacteriophage P1 gene 10 encodes a trans-activating factor required for late gene expression.

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Both control and Roux-en-Y gastric bypass operated study group had a pair of electrodes placed on three points of the remaining stomach: fundus, body and antrum. The aim of this study was to investigate if a CPP-ACP-containing paste would neutralize acidic challenges in dental plaque following sucrose rinse.

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To evaluate the importance of fluid balance and changes in extravascular lung water (EVLW) on survival in the ICU and short-term outcome in patients with pulmonary edema. Comparative transcriptomics in Yersinia pestis: a global view of environmental modulation of gene expression. shocks was repeated after 2 hr in nine dogs and after more than 24 hr in three dogs. 12 / 16 patients had a complete regression of symptoms, 1 / 16 patients had partial regression and 3 / 16 patients had no improvement.

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First-generation meronts of Eimeria bovis were found in the mesenteric lymph nodes (MLNs) of three of four calves examined during the first 18 days of primary experimental infection. Immunohistochemical analysis of the cerebral small arteries in affected persons showed increased expression of the extra domain-A region of fibronectin and versican in the thickened tunica intima and of TGF-beta1 in the tunica media. The ability of proteolytic enzymes from various sources, especially from lactic acid bacteria, to release bioactive peptides and the physiological and biotechnological significance of these peptides in dairy products are reviewed. Using smaller-size extended-range nozzles above the recommended pressure range resulted in lower deposits, especially inside the crop canopy. A retrospective review was performed on 13 children (August 2005 to April 2010) who were patients undergoing lymphangioma resection with postoperative VAC therapy.

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In the absence of a flexible paediatric fibrescope, a rigid endoscope (2.7 mm, 70 degrees lateral illumination) was passed orally to provide a view of the glottis on the monitor screen. Schlafen 3 is a novel gene recently associated with cellular differentiation.

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